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Is Myo Inositol For Depression?

Is Myo Inositol For Depression? 1

In this post we explore myo inositol for depression. If you regularly feel like the weight of the world is resting on your shoulders, then you may be struggling with depression or depressive episodes. Dealing with depression is no easy feat. It can disrupt your life significantly and impact your relationships with the people you love and live with. 

But, it is essential not to lose hope. There are lots of tools, resources, and support groups available that can help you address your depression in a way that is most comfortable and makes the most sense for you. 

If you are living with someone with depression, you know how hard it can be to watch them struggle every single day. 

If you, or your loved one, have tried a lot of treatments for depression, you may be feeling like there are no workable and viable solutions. 

There are natural supplements available that may help, especially given the fact that they are unlikely to impact the body’s physiology in the same way that pharmaceuticals can. 

While supplements should not replace prescription medication and medical advice, they can be taken in support of regulating hormone production and mental cognition. 

If you are looking for natural ways to manage depression, you might consider trying Inositol in conjunction with ongoing lifestyle and behavioural changes. 

Benefits of Myo-Inositol

Inositol is a naturally occurring phospholipid that is an effective therapy for regulating insulin resistance, controlling PCOS symptoms, improving fertility, and improving mental health. Some benefits of taking myo-Inositol for mental health include improved symptoms for obsessive-compulsive disorder (OCD), anxiety, depression, and panic disorder. 

Inositol has several purposes, but largely it is effective at regulating insulin production. Because it can target insulin resistance and hormone production, it also affects other hormonal balances in the body. 

Inositol has several evidence-based health benefits, including:

  • Improved fertility
  • Regulation of PCOS (polycystic ovarian syndrome) symptoms
  • Regulation of blood sugar
  • Improved insulin sensitivity
  • Reduced depression
  • Improved overall cognitive health
  • Reduced anxiety
  • Reduced waistline or weight

Four main conditions might lead someone to Inositol: mental health issues, insulin sensitivity or diabetes, PCOS, and infertility. If you have any of these conditions or a combination of them, then you might want to consider the health benefits listed above. And, with virtually no side effects, most people taking Inositol will not only remain in good health but will also show health improvement. 

Inositol and Depression

For decades, Inositol has believed to be effective at treating cognitive health like bipolar, depression, anxiety, and much more. Research has found that when treated for bipolar disorder with Inositol at a 12 g dosage for six weeks, 50% of the participants showed improvements in baseline cognitive health. 

Other double-blind studies have found 12g of Inositol to be effective at treating obsessive-compulsive disorder (OCD) and panic disorder. Some researchers suggest that Inositol significantly affects cognitive health because it is a biomarker for specific mental health issues, like major depressive disorder (MDD). Deficient levels of Inositol in the brain might be associated with adverse cognitive decline. 

Unfortunately, studies are still murky around how effective Inositol might be for depression. No matter what you decide, always consult with your doctor first before considering Inositol as a supplement to replace any type of prescriptions. You might need to take a mega-dose of Inositol as well (around 12 grams per day), and getting this amount would require that you purchase the pill form and purchase bulk-sized orders from a reliable company like Inositol Australia. 

Some sources suggest that Inositol can help someone with depression for a while, but then those effects shift after a few weeks; so the treatment can be inconsistent. Speak with your doctor before testing any large doses. 

Inositol is not a cure for depression, bipolar disorder, OCD, or panic disorder, but numerous studies over several decades show that there is some obvious link. Taking Inositol in tandem with medically supervised treatments may help individuals see significant improvement in their condition. 

If you are receiving treatment for depression, and are not seeing or feeling any improvements, talk to your doctor about adding Inositol to your supplemental routine. 

Using Inositol for Cognitive Health

Inositol is also known as vitamin B8. Inositol is produced naturally in the body after carbohydrates are consumed, and it is found naturally in many of the foods we eat. The U.S. Department of Agriculture does not consider vitamin B8 or Inositol to be an essential nutrient. However, on average, approximately 1 gram of B8 is consumed daily naturally through our diet.

The most common plants and animals that Inositol is found in include:

  • Nuts
  • Whole grains
  • Legumes

There are different forms that Inositol might appear as, called isomers, but the two most common are Myo-Inositol and D-chiro-inositol. Both Myo-Inositol and D-Chiro in prescription dosages have been shown to improve the effects of PCOS and fertility. Therapeutic dosages of Myo-Inositol and D-Chiro individually, as well as in combination, showed positive results at improving menstrual regularity, metabolic parameters, endocrine parameters, insulin resistance, reducing acne in some people, and lowering weight. 

Unfortunately, the dosage that should be taken for regulating cognitive health is higher than average. Doses for PCOS, for example, are 4 grams per day but recommended doses for mental health conditions like depression and bipolar disorder are at 12 grams per day. Luckily, Inositol is extremely safe, and over the counter, supplements can be taken by anyone for improved daily living. 

If you are taking Inositol for depression, reassess your dose after 4-6 weeks, and also be sure to speak with your doctor about monitoring its effectiveness.

Consider a powder-based Inositol supplement. This way, you can test out the supplement to see if it provides your body with the balance that it needs. In using the powder form, you will have more control over the dosage size, and you will know that the product you are getting is organic and all-natural. 


Benjamin, J., Agam, G., Levine, J., Bersudsky, Y., Kofman, O., Belmaker, R. H. (1995). “Inositol Treatment in Psychiatry.” Psychopharmacology Bulletin.

Chengappa, K. R., Levine, J., Gershon, S., Mallinger, A. G., Hardan, A., Vagnucci, A., & Kupfer, D. J. (2000). Inositol as an add‐on treatment for bipolar depression. Bipolar Disorders, 2(1), 47-55.

Chiappelli, J., Rowland, L. M., Wijtenburg, S. A., Muellerklein, F., Tagamets, M., McMahon, R. P., & Hong, L. E. (2015). Evaluation of Myo-inositol as a potential biomarker for depression in schizophrenia. Neuropsychopharmacology, 40(9), 2157-2164.

Formuso, C., Stracquadanio, M., & Ciotta, L. (2015). Myo-inositol vs. D-chiro inositol in PCOS treatment. Minerva ginecologica, 67(4), 321-325.

Fux, M., Levine, J., Aviv, A., & Belmaker, R. H. (1996). Inositol treatment of obsessive-compulsive disorder. American Journal of Psychiatry, 153(9), 1219-1221.

Inositol Australia. (2020). Inositol Powder For Fertility

Tremblay, S. (2020). Vitamin B-8 Food Sources & Benefits.

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